Trained in etching at the Centre genevois de gravure contemporaine and then at the École Supérieure des Beaux-Arts of Geneva, he began a major production of engravings and linocuts. From the 90s, gradually evolving from a discourse linked to the intimate sphere to a discourse involving society as a whole, he developed an ensemble of installations and sculptures confronting individuals with their role as citizens, constrained between protection and control. Throughout his career, Fabrice Gygi has sporadically used performance as a perpetual exploration of the limits of his body. Borrowing from a minimalist formal vocabulary, he draws inspiration from urban infrastructures as well as everyday and nomadic objects, which he diverts from their primary functions thus manifesting ambiguity as a source of tension.

From the early 2010s, Fabrice Gygi initiates a rupture in his work by abandoning the creation of installations. Though the production of jewelry, then of sculptures and bas-reliefs with geometrical elementary forms, he focuses on the search for abstract and pure lines. At the same time, he began to work on large format watercolors. With a perfectly geometric composition, these watercolors on paper offer a limited chromatic range and once again reveal a tension between the material, its control and rigor of its use. Fabrice Gygi explores the technique of oil painting, freeing himself from the perfect geometry of his watercolors while still weaving lines in an abstract mesh of bright colors.

In September 2021, Gygi is awarded the Prix de la Société des Arts de Genève / Visuals Arts / 7th edition,on the occasion of his solo exhibition.

Major institutional exhibitions by Fabrice Gygi include: MAMCO, Geneva (2021; 2015; 2004); Centre d'art contemporain Les Eglises, Chelles (2013); Centre Culturel Suisse, Paris (2013); Instituto Svizzero di Roma, Rome (2010); Magasin 3, Stockholm (2006); Orange County Museum of Art, Newport Beach (2005); Kunstmuseum St. Gallen, St. Gallen (2005); Museum of Contemporary Art, Tucson (2001).

His work was placed in the center of group shows in several international institutions such as the Kunstmusem Olten, Olten (2018); Musée d'Art Moderne de Paris, Paris (2017); Kunsthaus Zürich, Zürich (2015); Swiss Institute, New York (2015); Palais de Tokyo, Paris (2011); Musée d’Art Contemporain de Lyon, Lyon (2007); Migros museum für gegenwartskunst, Zürich (2007); Museum Ludwig, Köln (2005); Museo Nacional Reina Sofia, Madrid (2003); 25^th Biennial of Ljubljana, Ljubljana (2003); Villa Medici, Rome (2002); Kunsthaus Bregenz, Bregenz (2000); MoMA PS1, New York (1998); Kunsthalle Bern, Bern (1996).

In 2009, he was invited to represent Switzerland at the 53^rd International Art Biennial in Venice. He also took part in the São Paulo Biennial in 2002.

Fabrice Gygi’s works were acquired by numerous collections including the MAMCO, Geneva; Mudac, Lausanne; Migros Museum, Zürich; M KHA, Antwerp; Magasin 3, Stockholm; Musée National d'Art Moderne, Centre Georges Pompidou, Paris; FRAC Ile de France — Le Plateau, Paris; FRAC Normandie — Rouen and the Centre national des arts plastiques, Paris.